Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
GPCRs that induce myofiber hypertrophy. Four GPCRs (Fzd7, β2-AR, CRFR2, and LPA receptor) have been shown to stimulate hypertrophy in myotubes and/or myofibers. Cognate ligands are italicized. A partial view of the known signaling mediators is shown. CRFR2 stimulates myofiber growth by an uncharacterized effector pathway. β2-AR also induces fiber type transitions to fast-twitch fibers (not shown).
