Table 1.
Comparison Between Controls and Patients |
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---|---|---|---|---|
Demographic Features | Controls | Patients | P Value Before Adjusting for Age and BMIa | P Value After Adjusting for Age and BMIb |
Age, yr | 37.9 ± 4.9 | 54.0 ± 3.0* | NA | NA |
BMI, kg/m2 | 25.1 ± 1.0 | 30.7 ± 1.6* | NA | NA |
Number of vaginal deliveries | 0 | 2.4 ± 1.3 | ||
Anal manometry | ||||
Anal resting pressure | 92 ± 7 | 53 ± 6c | <0.001 | 0.02 |
Anal squeeze pressure | 203 ± 12 | 108 ± 14c | <0.001 | 0.006 |
Anal sphincter EMGd | ||||
Rest, no. of motor units | 6.8 ± 0.6 | 5.1 ± 0.4 | 0.07 | 0.03 |
Rest, motor unit duration, ms | 5.5 ± 0.4 | 6.6 ± 0.4 | <0.05 | 0.71 |
Rest, polyphasic motor units, % | 14 ± 2 | 22 ± 2 | 0.07 | 0.52 |
Squeeze, no. of motor units | 4.8 ± 0.3 | 4.2 ± 0.3 | 0.28 | 0.41 |
Squeeze, motor unit duration, ms | 4.6 ± 0.4 | 6.5 ± 0.5 | 0.003 | 0.11 |
Squeeze, polyphasic motor units, % | 9 ± 2 | 16 ± 3 | 0.09 | 0.44 |
Rank sum test for association of subject status with specific feature.
Multiple variable regression model to assess association of subject status with specific feature adjusting for age and body mass index (BMI).
P < 0.05 vs. controls.
Values are averaged across all sites and also across multiple maneuvers during squeeze, in each patient.
Quantitative analysis.