Table 3.

Effect of R-568 in reducing forskolin-induced ΔI_sc in the colon

	ΔIscFSK, μA/cm2
	Absence of TTX		Presence of TTX
	Proximal	Distal	Proximal	Distal
Control	59 ± 16 (9)	37 ± 8 (9)	33 ± 9 (8)†	13 ± 5 (8)†
R-568	6 ± 5 (9)*	5 ± 2 (9)*	27 ± 7 (8)nsNS	6 ± 4 (8)nsNS

Data shown are means ± SE (n). ΔI_sc^FSK, forskolin-induced ΔI_sc.

^*P < 0.01 vs. control; ns P > 0.05 vs. control;

^†P < 0.05 vs. absence of TTX. NS, P > 0.05 vs. absence of TTX.