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. Author manuscript; available in PMC: 2012 Jul 25.
Published in final edited form as: J Biophotonics. 2011 Nov 28;5(1):25–32. doi: 10.1002/jbio.201100102

Figure 3.

Figure 3

(online color at: www.biophotonics-journal.org) VPA imaging and spectroscopy of arterial plaque in the presence of blood. (A) Schematic for VPA imaging of an artery through whole blood. (B) 3-D imaging of arterial plaque by 1730 nm excitation. Lumen and blood are indicated with red arrows. To precisely control the thickness at 0.5 mm, the blood was sandwiched between two cover glasses. As the result, the ultrasound signal from the blood layer was reflected by the glasses for multiple times, which generated an interference pattern of the signal from blood. (C) VPA image at selected x-z plane under 1730 nm excitation. (D) VPA image at selected x-z plane under 1210 nm excitation. (E) VPA spectrum taken at the lipid deposition pointed by red arrow in (C). Scale bar: 1 mm.