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. 2012 May 11;303(2):L161–L168. doi: 10.1152/ajplung.00348.2011

Fig. 4.

Fig. 4.

A: time course of the mean change in [Ca2+]i from baseline (Δ[Ca2+]i) induced by hypoxia (4% O2) after treatment with ryanodine (10 μM) or xestospongin C (0.1 μM) beginning at 2 min in rat distal PASMC perfused with normal KRBS. Untreated cells served as controls. B: mean peak changes in [Ca2+]i (Δ[Ca2+]i) induced by hypoxia (4% O2) in rat distal PASMC perfused with Ca2+-free KRBS after treatment with ryanodine (10 μM) or xestospongin C (0.1 μM). Untreated cells served as controls.