Fig. 2.

A: primary prostate tumor weight of C57/BL-6 male mice randomized to voluntary wheel running or sedentary control on day 14 (n = 4/group), day 36 (n = 4/group), day 42 (n = 4/group), and day 53 (n = 18–20/group). Mean primary prostate weights with SE (error bars) are shown. Statistical significance was determined by one-way repeated ANOVA (P > 0.05). B: total weight of prostate tumor metastasis of C57/BL-6 male mice randomized to voluntary wheel running or sedentary control (n = 6–8/group across all study timepoints). Total prostate tumor metastasis with SE (error bars) are shown. Statistical significance was determined by an independent samples t-test. C: total number of prostate tumor metastasis of C57/BL-6 male mice randomized to voluntary wheel running or sedentary control (across all study time points). Statistical significance was determined by a Wilcoxon Rank-Sums test.