Table 3.
Prevalence of Cardiac Death High Risk ECG Features in Patients with Ischemic Cardiomyopathy (n = 198)
| Parameter | Mean ± SD (Range) | Cutoff Value for Risk of Cardiac Death | Abnormal n (%) | Prevalence*(%) |
|---|---|---|---|---|
| All patients (n = 198) | ||||
| Atrial fibrillation (count) | – | Present 4 | 20 (10.1) | 10.1 |
| Nonsustained VT (count) | 4.9 ± 11.1 (0‐61) | 1 episode of ≥3 consecutive PVCs 15 | 94 (47.5) | 47.5 |
| Fragmented QRS (count) | 1.5 ± 2.1 (0‐8) | 2 leads with fQRS in same territory 31 | 102 (51.5) | 51.5 |
| Pacing (% of recording) | 77.2 ± 37.8 (1‐100) | Persistent RV pacing 18 | 9 (4.5) | 4.5 |
| Excluding Persistent RV & BiV pacing (n = 155) | ||||
| Q Waves (count) | 1.8 ± 2.0 (0‐9) | One Q wave in each territory 5 | 15 (9.7) | 7.6 |
| Left ventricular hypertrophy (count) | – | Present per Cornell 19 | 16 (10.3) | 8.1 |
| Left Bundle Branch Block (count) | – | Present per AHA 20 | 11 (7.1) | 5.6 |
| Excluding LBBB or persistent RV & BiV pacing (n = 144) | ||||
| Dynamic ST depression (count) | – | >1 mm for 1 min in 2 consecutive leads 21 | 69 (47.9) | 34.8 |
| Excluding atrial fibrillation or persistent RV & BiV pacing (n = 141) | ||||
| Elevated minimum HR (beat/min) | 52 ± 10 (22‐91) | ≥65 22 | 12 (8.5) | 6.1 |
| Frequent premature Ventricular complexes (count) | 250 ± 155 (0‐880) | ≥10 PVCs per hr 15 | 62 (44.0) | 31.3 |
| Prolonged QRS duration (ms) | 125 ± 27 (67‐210) | >110 12 | 94 (66.7) | 47.5 |
| Low heart rate variability | 22 (15.6) | 11.1 | ||
| RR50 (%) | 12 ± 19 (0‐91) | <0.75 23 ‐ 24 or | ||
| rmsSD (ms) | 73 ± 67 (1‐591) | <15 23 ‐ 24 or | ||
| SDNN (ms) | 110 ± 52 (0‐377 | <50 23 ‐ 24 | ||
| Excluding atrial fibrillation, LBBB or persistent RV & BiV pacing (n = 130) | ||||
| Prolonged QTc (ms) | 447 ± 40 (350‐561) | >450 men or >470 women 2 | 32 (24.6) | 16.2 |
| Steep QT/RR slope (value) | 0.21 ± 0.12 (‐0.4‐0.9) | >0.22 13 | 49 (37.7) | 24.7 |
| Excluding atrial fibrillation, LBBB, persistent RV & BiV pacing, or wide (≥120ms) QRS complexes (n = 84) | ||||
| Wide QRS‐T angle (degrees) | 122 ± 38 (12‐176) | >100 7 | 61 (72.6) | 30.8 |
| Total | ||||
| Number of assessable features per patient | 11.7 ± 4.5 (4‐15) | – | – | – |
| Number of positive features per patient | 3.4 ± 1.8 (0‐8) |
HR = heart rate; VT = ventricular tachycardia; RV = right ventricle; BiV = biventricular; LBBB = left bundle branch block. (*) Prevalence is adjusted to the overall sample (n = 198).