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. 2012 Apr 11;108(2):595–609. doi: 10.1152/jn.00859.2011

Fig. 8.

Fig. 8.

Firing frequency adaptation in different electrophysiological classes of pyramidal cells in monkey DLPFC. A–D: plots of instantaneous spike frequencies in the sequential sweeps for representative examples of pyramidal cells of 4 different electrophysiological classes. Note that with near-threshold depolarizing current steps, both classes of RS cells (A and B) display nonadapting or weakly adapting firing pattern, whereas the LTS cells (C) exhibit strong firing frequency adaptation; with larger depolarizing current steps, plots for RS and LTS cells look alike. In contrast, in IM cells (D), the initial spike doublet is followed by an almost nonadapting firing with the full range of depolarizing current steps, forming the characteristic plot. E: bar graph summarizing the mean values of early and late firing frequency adaptation (FFA) in the 4 classes. Note the different ratio between FFA_early and FFA_late in IM and LTS cells.