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Bevacizumab treatment reduced vessel density and dysplasia in the adult mouse bAVM model. (A) Representative images show lectin-stained vessels. There are fewer irregular shaped large vessels (arrows) in the bevacizumab treated group as compared to trastuzumab. Scale bar: 50 μm. (B) Bar graph shows quantification of vessel density and dysplasia index. Bevacizumab treatment reduced vessel density (*p=0.01) and dysplasia index (*p=0.02) as compared to trastuzumab treatment.
