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Comparison of I–V data for a representative break-junction before and after the surface modification and exposure to EGFR: (a) Anti-EGFR aptamer chip shows current increase due to the capture of EGFR bridging the nanogap; (b) Mutant aptamer functionalized control chip shows no change in conductivity, inset shows data for control chip with no aptamer and thus no change in conductivity. Both controls show no capture of EGFR.
