Skip to main content
. 2012 Apr 20;10:2. doi: 10.1186/1479-0556-10-2

Table 4.

GAG concentration in brains of mice treated with gene therapy

# Groups Total GAG Mean ± SD DS-HS (%)a
11
WT 20w
1140.4
1566 ± 419
6.2
12
WT 20w
1281.2
 
9.9
13
WT 20w
1997.3
 
32.1
14
WT 20w
1849.6
 
29.0
1
WT 29w
NE
1907 ± 212
23.8
2
WT 29w
2057.0
 
NE
3
WT 29w
1757.3
 
9.8
15
KO 20w
2741.0
2443 ± 470
40.0
16
KO 20w
2889.3
 
48.8
24
KO 20w
1850.0
 
50.0
25
KO 20w
2290.0
 
48.2
4
KO 29w
4345.0
3234 ± 1287
49.8
5
KO 29w
3235.5
 
47.7
26
KO 29w
1429.0
 
43.5
27
KO 29w
3930.0
 
57.3
19
KO/IDUA 20w
1220.2
2065 ± 487
37.3
20
KO/IDUA 20w
2323.0
 
42.1
21
KO/IDUA 20w
2404.4
 
46.1
22
KO/IDUA 20w
2296.0
 
49.2
23
KO/IDUA 20w
2083.0
 
49.4
8
KO/IDUA 29w
1656.0
1509 ± 364
42.6
9
KO/IDUA 29w
1778.9
 
39.8
10 KO/IDUA 29w 1094.2   55.6

Total GAG is expressed in μg/g dry tissue; (#) Animal identification number;

a % = [DS-HS]/[Total GAG] * 100; NE = non-evaluated; w = week-old.