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. 2012 Jul 25;7(7):e42031. doi: 10.1371/journal.pone.0042031

Table 1. Summary of studies evaluating the association between Adenovirus 36 (Ad36) infection and obesity/metabolic markers in humans.

First author, year Type ofsubject Country Parameters Assessmentof obesity Number of subjects Mean age (yrs) Female (%) Mean BMI(kg/m2) Participants Prevalence of Ad36 infection
Atkinson, 2005 (5) Adults USA Obesity, BMI, TG, TC BMI≧30 502 40.9 78 38.0 360 obese and 142non-obese adults Obese 30% Non-obese 11%
Atkinson, 2005 (5) Adults USA BMI, TG, TC NA 56 NA 79 25.3 28 sets of twins Overall 22%
Trovato, 2009 (6) Adults Italy Obesity, BMI, TG, TC, LDL,HDL, SBP BMI>30 203 45.9 64 27.7 68 obese and 135non-obese adults Obese 65% Non-obese 33%
Atkinson, 2010 (7) Children South Korea TC, WC, SBP, BG NA 84 14.8 16 NA 83 obese or overweightchildren and one non-obese child Overall 30%
Broderick, 2010 (8) Adults USA Obesity BMI>29 293 NA 30 NA 146 obese and 147non-obese adults Obese 34% Non-obese 39%
Gabbert, 2010 (9) Children USA Obesity, BMI, WC BMI>95th percentile 124 13.4 44 27.9 67 obese and 57 non-obese children Obese 22% Non-obese 7%
Na, 2010 (10) Children South Korea Obesity, BMI, TG, TC, WC,LDL, HDL, SBP, BG BMI≧30 318 11.7 42 24.1 259 obese and 59 non-obese children Obese 29% Non-obese 14%
Trovato, 2010 (11) Adults Italy BMI, TG, TC, LDL, HDL, BG NA 179 45.7 65 27.4 65 NAFLD and 114 non-NAFLD adults NAFLD 32% Non-NAFLD 46%
Goossens, 2011 (12) Adults Netherlands and Belgium Obesity, BMI NA 509 NA NA 26.8 136 obese, 281 non-obese,and 92 BMI-unknownadults Obese 6% Non-obese 4%
Na, 2012 (13) Adults South Korea Obesity, BMI, TG, TC, WC,HDL, SBP, BG BMI≧25 540 44.3 50 24.0 180 obese and 360non-obese adults Obese 30% Non-obese 36%
Trovato, 2012 (14) Adults Italy BMI, TG, TC, LDL, HDL, BG NA 62 50 56 30.3 62 NAFLD adults Overall 40%

BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); TG, triglycerides; TC, total cholesterol; LDL, low density lipoprotein; HDL, high density lipoprotein; BG, blood glucose; NAFLD, Non-alcoholic fatty liver disease; SBP, systolic blood pressure; WC, waist circumstance; NA, not available;