Table 1. Summary of studies evaluating the association between Adenovirus 36 (Ad36) infection and obesity/metabolic markers in humans.
First author, year | Type ofsubject | Country | Parameters | Assessmentof obesity | Number of subjects | Mean age (yrs) | Female (%) | Mean BMI(kg/m2) | Participants | Prevalence of Ad36 infection |
Atkinson, 2005 (5) | Adults | USA | Obesity, BMI, TG, TC | BMI≧30 | 502 | 40.9 | 78 | 38.0 | 360 obese and 142non-obese adults | Obese 30% Non-obese 11% |
Atkinson, 2005 (5) | Adults | USA | BMI, TG, TC | NA | 56 | NA | 79 | 25.3 | 28 sets of twins | Overall 22% |
Trovato, 2009 (6) | Adults | Italy | Obesity, BMI, TG, TC, LDL,HDL, SBP | BMI>30 | 203 | 45.9 | 64 | 27.7 | 68 obese and 135non-obese adults | Obese 65% Non-obese 33% |
Atkinson, 2010 (7) | Children | South Korea | TC, WC, SBP, BG | NA | 84 | 14.8 | 16 | NA | 83 obese or overweightchildren and one non-obese child | Overall 30% |
Broderick, 2010 (8) | Adults | USA | Obesity | BMI>29 | 293 | NA | 30 | NA | 146 obese and 147non-obese adults | Obese 34% Non-obese 39% |
Gabbert, 2010 (9) | Children | USA | Obesity, BMI, WC | BMI>95th percentile | 124 | 13.4 | 44 | 27.9 | 67 obese and 57 non-obese children | Obese 22% Non-obese 7% |
Na, 2010 (10) | Children | South Korea | Obesity, BMI, TG, TC, WC,LDL, HDL, SBP, BG | BMI≧30 | 318 | 11.7 | 42 | 24.1 | 259 obese and 59 non-obese children | Obese 29% Non-obese 14% |
Trovato, 2010 (11) | Adults | Italy | BMI, TG, TC, LDL, HDL, BG | NA | 179 | 45.7 | 65 | 27.4 | 65 NAFLD and 114 non-NAFLD adults | NAFLD 32% Non-NAFLD 46% |
Goossens, 2011 (12) | Adults | Netherlands and Belgium | Obesity, BMI | NA | 509 | NA | NA | 26.8 | 136 obese, 281 non-obese,and 92 BMI-unknownadults | Obese 6% Non-obese 4% |
Na, 2012 (13) | Adults | South Korea | Obesity, BMI, TG, TC, WC,HDL, SBP, BG | BMI≧25 | 540 | 44.3 | 50 | 24.0 | 180 obese and 360non-obese adults | Obese 30% Non-obese 36% |
Trovato, 2012 (14) | Adults | Italy | BMI, TG, TC, LDL, HDL, BG | NA | 62 | 50 | 56 | 30.3 | 62 NAFLD adults | Overall 40% |
BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); TG, triglycerides; TC, total cholesterol; LDL, low density lipoprotein; HDL, high density lipoprotein; BG, blood glucose; NAFLD, Non-alcoholic fatty liver disease; SBP, systolic blood pressure; WC, waist circumstance; NA, not available;