Table 2. Additional virulence-related proteins identified among the proteins predicted to be secreted by A. actinomycetemcomitans strain D7S.

GI accession number D7S	Protein namea)	Signal sequenceb)	COG functional classificationc)
Earlier reported association with virulence-related activity in A. actinomycetemcomitans d)
293391897	Autotransporter adhesin Aae	y	uncategorized
293391439	Chb proteine)	y	Carbohydrate metabolism and transport
293390626 293390627 293390628f)	Extracellular matrix protein adhesin A	n	Intracellular trafficking and secretion
Earlier reported association with virulence-related activity in other organisms but not yet in A. actinomycetemcomitans d)
293391047	Lipoprotein VacJ	y	Cell wall/membrane/envelope biogenesis
293391875	Opacity-associated protein OapA	n	Chromatin Structure and dynamics
293391876	Opacity-associated protein OapB	y	uncategorized
293391443	Outer membrane antigenic lipoprotein B	y	Cell envelope biogenesis, outer membrane

^a)Full name of D7S genome database entry.

^b)Presence (y) or absence (n) of N-terminal signal sequence.

^c)Functional classification according to the database of Clusters of Orthologous Groups of proteins (COGs).

^d)See text.

^e)Also referred to as dispersin B or DspB.

^f)Assigned as three separate proteins in the D7S genome database used.