Table 5. Addition of family history information to genetic risk scores.

	NRI			IDI
	Value	SE	p	Value	p
FRS+FH
Cases	0.031	0.025	0.169	0.008	0.0005
Non-cases	0.053	0.026	0.044	0.001	0.469
	0.088	0.036	0.016	0.006	0.018
FRS+FH+GRS1
Cases	0.065	0.035	0.065	0.006	0.0065
Non-cases	0.033	0.031	0.033	0.001	0.588
	0.098	0.042	0.019	0.007	0.003
FRS+FH+GRS2
Cases	0.142	0.041	0.0005	0.018	0.001
Non-cases	0.011	0.039	0.787	0.001	0.683
	0.132	0.054	0.015	0.018	0.0025

Reclassification results comparing a baseline model including family history (FH); to models including genetic risk scores for men aged 50–59.