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. 2012 Jul 25;7(7):e41834. doi: 10.1371/journal.pone.0041834

Figure 7. ABC294640 attenuates necrosis and apoptosis after liver transplantation.

Figure 7

Livers were harvested at 18 h after transplantation (TX) or sham-operation (Sham). Liver slices were stained with H&E for assessment of necrosis. Representative images are shown in A to C. Arrows identify the necrotic areas. The bar is 100 µm. Necrotic areas were quantified by image analysis of 10 randomly selected fields (D). Apoptosis was assessed by TUNEL staining, and TUNEL-positive cells were counted in 10 randomly selected fields (E). Cleaved caspase-3 and actin were detected by immunoblotting (F). ABC, ABC294640; a, p<0.05 vs sham; b, p<0.05 vs the TX group (n = 4 per group).