Table 2. Prospective association of unadjusted (for season) 25(OH)D3 concentrations (assessed at mean age 9.9 years) with psychotic experiences (PLIKS) (assessed at age 12.8 years). N = 3182 (208 cases with suspected/definite PLIKS) and N = 2974 (142 cases with definite PLIKS; in these analyses suspected cases are removed from the analyses).
Exposure | Outcome | Odds ratio of outcome per doubling of exposure (95%CI) | |||
Model 1 | Model 2 | Model 3 | Model 4 | ||
25(OH)D3 | Suspected/definite PLIKS | 0.88 (0.79, 0.97) | 0.87 (0.78, 0.96) | 0.87 (0.77, 0.96) | 0.88 (0.79, 0.98) |
Definite PLIKS | 0.88 (0.79, 0.97) | 0.86 (0.78, 0.95) | 0.87 (0.78, 0.95) | 0.88 (0.78, 0.98) |
Model 1 is unadjusted (25(OH)D3 is adjusted for age and gender).
Model 2 as Model 1 plus adjustment for ethnicity, time spent outdoors during summer (age 8.5 years), use of sunblock, hat, covering clothing, avoidance of midday sun and BMI.
Model 3 as Model 2 plus adjustment for head of household social class, mother’s and partner’s education, family history of mental health problems and puberty stage.
Model 4 as Model 3 plus adjustment for 25(OH)D2, phosphate, albumin-adjusted calcium and parathyroid hormone.