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. 2012 Jul 25;7(7):e40999. doi: 10.1371/journal.pone.0040999

Figure 7. A bifurcated signaling pathway is involved in PMA-mediated adhesion of monocytes.

Figure 7

PKC can activate LKB1/AMPK, leading to phosphorylation and activation of Syk, then Src and FAK subsequently. PKC-dependent ERK activation induces a coordinated signal for cytoskeleton rearrangement and cell adhesion.