Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul 25;7(7):e41275. doi: 10.1371/journal.pone.0041275

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Zhong, Gerges.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

(A) Representative images of immunogold-EM for endogenous CaMKII in dendritic spines of CA1 hippocampal neurons. Arrows indicate anti-CaMKII immunogold particles. Scale bar, 100 nm. (B) Cumulative probabilities of normalized radial distance. The distance of each gold particle from the plasma membrane (within the spine) was normalized (x axis) to the corresponding radius of the spine measured through that particle. CaMKII distribution within the spine is significantly different from a theoretical random distribution (n = 173, p<0.001). (C) Comparison of CaMKII and CaM distribution using cumulative probabilities of normalized radial distance. CaMKII and CaM show similar patterns of lateral distribution. The highest fraction of labeling for both occurs within 0.2 of the radial distance. (D) Vertical distribution of CaMKII and CaM with respect to PSD. The absolute distance between each gold particle to the PSD was measured. (E) Distribution of CaMKII between the different sub-compartments within the spine.