Table 3.
Uptake of [3H]-Riboflavin on RBE4 cells in presence of various concentrations of PTK and PKC pathway modulators in DPBS (pH 7.4) at 37° C. The uptake is expressed as percentage of control (DPBS). Each data point is expressed as mean ± standard deviation (n=4). P<0.01 is considered as statistically significant from control. NS represents not statistically significant from control.
| Pathway | Modulators | Uptake as % of control |
Statistics |
|---|---|---|---|
| PTK | Control Genistin (50 µM) Genistin (100 µM) Genistein (50 µM) Genistein (100 µM) Tyrphostin A25 (50 µM) Tyrphostin A25 (100 µM) |
100 ± 3 88 ± 3 91 ± 9 96 ± 3 96 ± 5 102 ± 2 101 ± 4 |
- NS NS NS NS NS NS |
| PKC | Control PMA (5 µM) PMA (10 µM) PMA (50 µM) |
100 ± 4 106 ± 1 101 ± 3 112 ± 3 |
- NS NS NS |