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. Author manuscript; available in PMC: 2013 Jul 25.
Published in final edited form as: J Am Chem Soc. 2012 Jul 5;134(29):12219–12229. doi: 10.1021/ja3041866

Figure 2.

Figure 2

Phylogenetic analysis of the superfamily of sugar phosphate cyclases. Boxed proteins are representatives of families of sugar phosphate cyclases being studied in this paper. Maximum likelihood analysis was carried out using MEGA5 software with a WAG amino acid substitution model and a discrete gamma distribution was used to model evolutionary rate differences among sites. The robustness of the trees was assessed by bootstrap analysis (100 replicates). The source and accession number of the proteins are listed in Table S1.