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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Invest New Drugs. 2011 Sep 7;30(5):1841–1848. doi: 10.1007/s10637-011-9745-y

Figure 6.

Figure 6

The caspase-9 specific inhibitor blocks apoptosis induced by cluvenone. PC3 cells were pre-treated with increasing concentrations of the caspase 9 inhibitor, Z-LEHD-FMK for 30 min prior to treatment with 1.5 μM cluvenone for 7 h. Control cells received 0.2% DMSO, cluvenone alone, or Z-LEHD-FMK alone. Apoptosis was measured by the Cell Death Detection ELISAplus kit. All conditions were performed in triplicate and error bars represent SD.