Table 2. Changes in Breslow thickness (log transformation) over time according to age, sex, and lesion location.

	Regression coefficient (95% CI)		P -value
Young
Males
Head and neck	−0.43	−0.66 to −0.20	<0.001
Trunk	−0.26	−0.37 to −0.14	<0.001
Upper extremities	−0.36	−0.56 to −0.16	<0.001
Lower extremities	−0.16	−0.41 to −0.1	0.2
Females
Head and neck	−0.21	−0.51 to 0.1	0.2
Trunk	−0.31	−0.45 to 0.17	<0.001
Upper extremities	−0.51	−0.70 to −0.32	<0.001
Lower extremities	−0.33	−0.46 to −0.19	<0.001
Elderly
Males
Head and neck	−0.35	−0.56 to −0.14	0.001
Trunk	−0.42	−0.60 to −0.25	<0.001
Upper extremities	−0.20	−0.47 to 0.1	0.2
Lower extremities	−0.28	−0.61 to 0.1	0.1
Females
Head and neck	−0.18	−0.44 to 0.1	0.2
Trunk	−0.36	−0.62 to −0.10	0.01
Upper extremities	−0.15	−0.37 to 0.06	0.2
Lower extremities	−0.13	−0.32 to 0.1	0.2
Overall
Males and females
All locations	−0.25	−0.30 to −0.20	<0.001