. 2012 Jun 21;107(3):491–500. doi: 10.1038/bjc.2012.272

Table 2. PIM inhibitor potentials, determined as the half maximal inhibitory concentration (IC₅₀) for two structurally independent PIM inhibitors in GC and non-GC-derived DLBCL cell lines.

	IC₅₀ 24 h (μℳ)		IC₅₀ 48 h (μℳ)
Cell line	K00486	Compound 20	K00486	Compound 20
SU-DHL-4	14.4	5.27	9.71	3.21
SU-DHL-6	12.1	3.29	8.40	2.35
SU-DHL-7	>100	>100	>100	>100
SU-DHL-10	6.2	2.65	3.77	1.95
HBL-1	33.8	10.6	18.34	9.70
U2932	24.5	8.79	8.62	5.88
OCI-Ly3	10.36	4.80	6.042	2.98
OCI-Ly10	>100	13.2	51.15	11.63

Abbreviations: DLBCL=diffuse large B-cell lymphoma; GC=germinal centre; IC₅₀=half maximal inhibitory concentration; PIM=proto-oncogene serine/threonine-protein kinase.

The data represent the mean of three independent experiments performed in quadruplicate.

Table 2. PIM inhibitor potentials, determined as the half maximal inhibitory concentration (IC50) for two structurally independent PIM inhibitors in GC and non-GC-derived DLBCL cell lines.

Table 2. PIM inhibitor potentials, determined as the half maximal inhibitory concentration (IC₅₀) for two structurally independent PIM inhibitors in GC and non-GC-derived DLBCL cell lines.