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. 2012 Jun 26;107(3):429–434. doi: 10.1038/bjc.2012.274

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Copyright © 2012 Cancer Research UK

From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Relationship between pharmacokinetic parameters of trifluorothymidine (TFT; C_max and AUC_inf) and the percent change of the neutrophil count of patients treated with 30–70 mg m⁻² per day of TAS-102 on day 12 in 1 course. (A) Relationship between TFT C_max and the percent change of the neutrophil count. (B) Relationship between TFT AUC_inf and the percent change of the neutrophil count. Each symbol denotes an individual value.