Table 2. Trends of prostate cancer incidence by disease grade and socio-economic circumstances from 1991 to 2007: joinpoint analysis.
| No. of incident cases (min–max) | EASR rate per 106 (min–max) | Annual percentage change (95% CI) | ||
|---|---|---|---|---|
| Overall incidence: 1991–2007 | ||||
| 1991–1996 | 635–943 | 43.8–69.2 | 8.4a | (3.5, 13.5) |
| 1996–1999 | 815–943 | 59.3–63.08 | –2.5 | (−19.3, 17.8) |
| 1999–2004 | 900–1263 | 63.08–93.43 | 7.7a | (1.9, 13.9) |
| 2004–2007 | 1016–1263 | 75.16–93.43 | –5.6 | (−13.4, 2.9) |
| Grade-specific overall incidence: 1997–2007 | ||||
| Low-grade (Gleason ⩽7) | ||||
| 1997–2004 | 435–783 | 31.16–58.25 | 7.86a | (4.3, 11.5) |
| 2004–2007 | 588–783 | 43.72–47.80 | −4.78 | (−15.3, 7.1) |
| High-grade (Gleason 8–10) | ||||
| 1997–2000 | 248–251 | 17.57–18.37 | 0.5 | (−18.2, 23.4) |
| 2000–2007 | 249–433 | 19.40–31.60 | 7.6a | (2.6, 12.8) |
| Deprivation-specific overall incidence: 1991–2007 | ||||
| Affluent (Depcat 1 and 2) | 100–250 | 46.35–120.13 | 5.28a | (3.8, 6.8) |
| Intermediate (Depcat 3, 4 and 5) | 339–736 | 42.42–96.76 | 4.05a | (3.0, 5.2) |
| Deprived (Depcat 6 and 7) | 177–277 | 47.70–75.85 | 1.33a | (0.1, 2.5) |
Abbreviations: EASR=European age-standardised rate; CIs=confidence intervals.
a
The average annual per cent change is statistically significant from 0.