Fig. 2.

Model—Consumption of Brassica vegetables may prevent vascular inflammation at atherosusceptible sites. Regions of arteries with relatively uniform geometry are protected from inflammation and atherosclerosis by high shear stress which activates Nrf2. By contrast, branches and bends that are exposed to low, oscillatory shear stress are susceptible to lesion formation. However, dietary consumption of Brassica vegetables may prevent branches and bends from inflammation by activating Nrf2 in endothelial cells