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Immunohistochemical staining of GLUT-1. Vemurafenib treatment induces decreases in both total and membrane GLUT-1 staining in A375 tumors but not in the resistant A375R1 line. Immunohistochemical staining for GLUT-1 in (A) A375 tumor xenografts and (B) A375R1-resistant xenografts.
