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. Author manuscript; available in PMC: 2013 Aug 30.
Published in final edited form as: Neuroscience. 2012 May 26;218:110–125. doi: 10.1016/j.neuroscience.2012.05.049

Figure 11.

Figure 11

The NTS projects to two blood pressure sensitive sites in the parabrachial nucleus: PBcl and PBel-outer. The former contains FoxP2+ neurons and the latter is made up of Lmx1b+ neurons. Most neurons localized in these two PB sites express Vglut2 mRNA, and thus, are presumed to be glutamatergic neurons. The Lmx1b+ neurons contain immunoreactive CGRP, while the presumed co-neurotransmitters of the FoxP2+ PBcl neurons are unknown. The FoxP2+ neurons in the PBcl were Fos-activated by hypotension, and the Lmx1b+ neurons of the PBelouter were activated by both hypotension and hypertension.