Table 1.
Antimicrobial susceptibility profile (MIC) and resistance genes of 16 E. coli O127a:K63 isolates and the ATCC 25922 controla
| Strain | MIC (mg/liter) |
Additional resistance | Mutation |
Other resistance genes |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| TX | CT | NX | CIP | NAL | gyrA | parC | parE | aac | blaCTX-M | ||
| E. coli O127a:K63 | >256 | >256 | >256 | >32 | >256 | LEV, AMC, SAM, AMP, CN, SXT, TE | S83L, D87N | S80I, A108V | S458A | aac(6′)-Ib-cr | blaCTX-M-15 |
| ATCC 25922 | 0.032 | 0.023 | 0.047 | 0.012 | 1.5 | ||||||
a
TX, ceftriaxone; CT, cefotaxime; NX, norfloxacin; CIP, ciprofloxacin; NAL, nalidixic acid; LEV, levofloxacin; AMC, amoxicillin; SAM, ampicil; AMP, ampicillin; CN, cidomycin; SXT, trimethoprim-sulfamethoxazole; TE, tetracycline. Mutations are denoted by the amino acid substitution and the position number (e.g., S83L denotes substitution of a serine by a leucine at position 83).