Table 2.
Proteins encoded by single-copy Bordetella PCR gene targetsa
| Protein encoded by target gene | Reference(s) |
|---|---|
| B. pertussis specific | |
| BP283 (thiolase) | 24 |
| BP485 | 24 |
| Shared among Bordetella species | |
| Adenylate cyclase | 4 |
| BP3385 | 9, 26 |
| Filamentous hemagglutininb | 14 |
| Flagellinb | 12 |
| Pertactin | 27, 36 |
| Pertussis toxinb | 11, 22, 31, 32 |
| Porinb | 6 |
| RecAb | 1, 8, 25 |
a
With the exception of the gene for pertussis toxin, PCR assays targeting the genes that encode these proteins have not been well validated.
b
Species-specific primers or PCR assays using postamplification differentiation of species have been described.