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. 2012 Jul 16;2012:467251. doi: 10.1155/2012/467251

Figure 1.

Figure 1

Body weights of Ts65Dn mice and wild-type littermate controls treated with vehicle or fluoxetine (2N, vehicle:  n = 8 mice; 2N, fluoxetine:  n = 11 mice; Ts65Dn, vehicle:  n = 7 mice; Ts65Dn, fluoxetine:  n = 7 mice). Two-way ANOVA with genotype and treatment as between-subjects factors showed significant main effects of genotype (ANOVA genotype F(1,29) = 7.37,  P = 0.01) and treatment (ANOVA treatment F(1,29) = 5.42,  P = 0.03). Posthoc analyses showed significantly lower body weights in fluoxetine-treated Ts65Dn mice compared to vehicle-treated Ts65Dn mice (Fisher's PLSD,  P = 0.04). Body weights in fluoxetine-treated 2N controls were not significantly different from 2N vehicle controls (Fisher's PLSD,  P = 0.19). Graph shows mean ± SEM. *denotes comparisons where  P < 0.05.  n.s. denotes comparisons where  P > 0.05.