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. 2012 Apr 12;9(74):2365–2382. doi: 10.1098/rsif.2012.0080

Table 2.

Optimal parameter sets: experimental data. The logic configurations (LCs), G, delays, τj, and discretization thresholds, Ti (0 < Ti < 1), yielding the top two fits of the 3-loop Arabidopsis logic model to experimental LUC time series recorded in LL. GOPT is the highest-scoring LC. GDE is the second highest-scoring LC, and is also the top-ranked configuration under the constraint that LHY represses TOC1 and TOC1 promotes LHY production. Note that GDE was previously identified as the LC giving the optimal fit to synthetic data generated by the equivalent DE model (cf. table 1).

G 10101011011 (GOPT) 10011011011 (GDE)
τ1 (h) 1.5 1.5
τ2 (h) 0 0
τ3 (h) 1.5 10.5
τ4 (h) 9 0
τ5 (h) 6 7.5
τ6 (h) 4.5 4.5
τ7 (h) 1.5 3
τ8 (h) 10.5 6
τ9 (h) 0 0
τ10 (h) 0 0
τ11 (h) 0 0
τ12 (h) 0 0
T1 0.30 0.35
T2 0.40 0.35
T3
T4 0.15 0.10
T5 0.50 0.45
p1 (h) 24 24
p2 (h) 24 24
p3 (h) 24 24
p4 (h) 24 24