Table 3. Decomposition of Enrichment Changes between DUD and DUD-E.
incremental change | all original | new style decoys | switch to new ligands | switch target preparation |
---|---|---|---|---|
decoys | DUD | DUD-E | DUD-E | DUD-E |
ligands | DUD | DUD | DUD-E | DUD-E |
receptor preparation | DUD | DUD | DUD | DUD-E |
average LogAUCa | 14.8 | 19.7 | 16.4 | 22.8 |
Over the 37 common targets (target-by-target data in Supporting Information Table S5).