Table 2.
Z-average diameters and polydispersity of control liposomes and peptide-conjugated liposomes
Preparation | Size (nm) | PDI |
---|---|---|
Control liposomes (no peptide) | 90 ± 5 | 0.220 ± 0.010 |
A371-PCL | 110 ± 10 | 0.170 ± 0.015 |
Scr-A371-PCL | 200 ± 100 | 0.270 ± 0.020 |
A415-PCL | 91 ± 10 | 0.420 ± 0.050 |
Scr-A415-PCL | 98 ± 20 | 0.264 ± 0.020 |
A417-PCL | 82 ± 20 | 0.373 ± 0.20 |
Note: Mean particle diameters (Zav) both with and without the targeting peptide were determined by dynamic light scattering and reveal the liposomes to be monodispersed, with narrow particle size distributions.
Abbreviation: PDI, polydispersity index.