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. Author manuscript; available in PMC: 2012 Jul 26.
Published in final edited form as: Stem Cells. 2010 Nov;28(11):2088–2098. doi: 10.1002/stem.532

Figure 3. Pathway-focused PCR array and qRT-PCR analyses of the expression of stem cell relevant genes in cells cultured as cardiospheres or monolayers.

Figure 3

A) Scatter plot demonstrating 13 out of the 84 stem cell genes up-regulated (red circles) in cells under cardiosphere culture condition. B) The names and fold changes of genes that are up- or down-regulated by greater than 4-fold above baseline in cardiosphere culture compared with monolayer culture. Furthermore, qRT-PCR analysis of 5 separate RNA samples from different human cardiac outgrowth cells confirmed that the expression of IGF-1 (C), TERT (D), and HDAC2 (E) is increased in cardiac stem cells cultured under cardiosphere condition when compared with monolayer condition.

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