Figure 6. Clock-rescue restores 24- but not 12-hour rhythms to circadian harmonics.

Panels A–C show the time course of Creld2 expression (a known 12-hour cycling gene) in wildtype (A), Clock-rescue (B) and Clock-mutant (C) livers. Panels D–F show a subset (N = 11) of wildtype 12-hour rhythms median-normalized and plotted as a heatmap (yellow = high expression, blue = low expression). Every line represents the temporal expression of one wildtype 12-hour cycling gene. Shaded bars above the heatmaps represent subjective day and night.