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. 2012 Jul 26;7(7):e41239. doi: 10.1371/journal.pone.0041239

Table 3. Posterior probability of event or non-event given the number of positive ratings.

Total Number of Adverse Event ratings out of 30 raters Probability that case truly is an Adverse Event
0 (0%) 0.0000
1 (3.3%) 0.0000
2 (6.6%) 0.0000
3 (9.9%) 0.0000
4 (13.2%) 0.0000
5 (16.5%) 0.0000
6 (20.0%) 0.0000
7 (23.3%) 0.0000
8 (26.7%) 0.0003
9 (30.0%) 0.0026
10 (33.3%) 0.0219
11 (36.7%) 0.1612
12 (40.0%) 0.6225
13 (43.3%) 0.9340
14 (46.7%) 0.9918
15 (50.0%) 0.9990
16 (53.3%) 0.9999
17 (56.7%) 1.0000
18 (60.0%) 1.0000
19 (63.3%) 1.0000
20 (66.7%) 1.0000
21 (70.0%) 1.0000
22 (73.3%) 1.0000
23 (76.7%) 1.0000
24 (80.0%) 1.0000
25 (83.3%) 1.0000
26 (86.7%) 1.0000
27 (90.0%) 1.0000
28 (93.3%) 1.0000
29 (96.7%) 1.0000
30 (100%) 1.0000

These estimates are from the latent class model that assumed a common sensitivity and specificity for all reviewers.