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. 2012 Jul 26;7(7):e42062. doi: 10.1371/journal.pone.0042062

Table 2. Distribution of CTLA-4 genotype among patients and controls included in the meta-analysis.

Studies Asthma Control HWE
11a 12b 22c 11 12 22 (P value)
+49 A/G
Nakao 27 52 41 32 107 61 0.189
Hizawa 40 178 121 40 140 125 0.935
Howard 76 82 19 39 72 23 0.297
Lee 15 24 49 8 29 49 0.238
Schubert 98 105 28 105 127 38 0.968
Jasek 66 101 52 33 48 21 0.645
Sohn 45 125 156 19 103 132 0.859
Chan 40 119 113 21 75 75 0.737
Daley 238 290 88 291 338 98 0.992
Oh 61 312 369 16 107 115 0.178
Undarmaa 1 49 153 123 43 155 138 0.959
Undarmaa 2 58 175 134 106 323 247 0.981
−318 C/T
Nakao 97 19 4 157 43 0 0.088
Hizawa 265 71 3 238 65 2 0.278
Howard 144 30 2 115 14 2 0.059
Lee 70 16 2 67 15 4 0.022
Jasek 172 44 3 79 22 1 0.694
Schubert 181 47 3 214 53 3 0.889
Qian 75 13 2 84 15 1 0.721
Sohn 247 77 2 199 54 1 0.182
Daley 537 100 5 616 128 7 0.902
Undarmaa 1 253 67 5 263 68 5 0.801
Undarmaa 2 284 78 5 512 153 11 0.911
DeWan 58 7 1 35 6 1 0.267
Anantharaman 350 128 12 343 134 13 0.799
−1147 C/T
Howard 108 46 2 97 18 2 0.295
Jasek 146 65 8 66 31 5 0.587
Chan 216 68 7 129 43 3 0.787
Daley 445 181 18 500 226 25 0.931
DeWan 52 13 1 29 12 1 0.853
Anantharaman 335 140 15 307 162 21 0.949
CT60 A/G
Chan 13 97 183 6 58 109 0.611
Berce 14 62 26 21 34 29 0.093
Daley 191 317 132 229 369 148 0.977
DeWan 8 31 27 4 19 19 0.810
Anantharaman 36 193 261 21 161 308 0.994
−1722 C/T
Daley 551 89 4 644 102 4 0.986
Sleiman 663 127 6 1666 308 14 0.954
Noguchi 340 463 135 862 1131 391 0.537
rs926169 A/C
Daley 236 307 100 282 356 111 0.937
Sleiman 284 382 127 743 945 300 0.987
Noguchi 135 455 342 336 1110 938 0.793
a

AA or CC;

b

AG, CT, or AC;

c

GG, TT or CC.

HWE, Hardy-Weinberg equilibrium.