Table 4. Microbiota composition of stool samples from different mouse groups analysed by quantitative PCR^a.

Bacterial group	Experimental groups
	SD	HFD		SD+B		HFD+B
	aMedian (IQR)	aMedian (IQR)	p- valueb	aMedian (IQR)	p- valuec	aMedian (IQR)	p- valued
Total bacteria	10.8 (10.6–11.1)	10.5 (10.3–10.8)	0.092	11.4 (11.3–11.6)	0.010*	11.0 (10.7–11.2.)	0.629
Lactobacillus group	9.9 (9.4–10.5)	9.4 (9.2–9.5)	0.040*	9.6 (9.3–9.8)	0.470	9.7 (9.5–10.1)	0.936
Bacteroides spp.	8.4 (8.3–8.6)	8.7 (8.3–9.0)	0.674	9.3 (9.1–9.5)	0.004*	9.0 (8.8–9.3)	0.016*
Bifidobacterium spp.	7.1 (6.8–7.2)	6.0 (5.9–6.3)	0.004*	8.1 (7.9–8.3)	0.013*	7.5 (7.0–7.7)	0.004*
C. leptum group	8.4 (8.3–8.6)	7.6 (7.5–7.7)	0.004*	9.6 (9.4–9.8)	0.004*	8.5 (8.1–8.7)	0.936
C. coccoides group	9.1 (8.6–9.3)	8.4 (8.2–8.5)	0.016*	9.9 (9.4–10.0)	0.054	9.6 (9.4–9.7)	0.036*
Enterobacteriaceae	7.3 (7.2–7.7)	8.1 (7.8–8.2)	0.019*	8.1 (7.6–8.2)	0.052	7.9 (7.5–8.0)	0.029*

SD: standard diet group (control) (n = 6); SD+B: standard diet group receiving a daily dose of 5.0×10⁸ CFU B. uniformis CECT 7771 by gavage for 7 weeks (n = 6); HFD: high fat diet group (n = 6); HFD+B: high fat diet group receiving a daily dose of 5.0×10⁸ CFU B. uniformis CECT 7771 by gavage during 7 weeks (n = 6).

^aData are expressed as median of log gene copy numbers of each bacterial group per gram of stools.

^bSignificant differences in log gene copy numbers of specific bacterial groups between SD and HFD mouse groups.

^cSignificant differences in log gene copy numbers of specific bacterial groups between SD and SD+B mouse groups.

^dSignificant differences in log gene copy numbers of specific bacterial groups between HFD and HFD+B groups.

^*Significant differences were established at P<0.05 by using Mann–Whitney U-test.