Table 3. Analysis of changes in serum lipid levels over time.

Lipids	n	month 12*	month 24	mean change	95% CI change	p-value
Mean TC (mg/dL)	209	159.5	163.9	4.4	−0.6–9.4	0.083
% elevated TC (>200 mg/dL)		12.1	21.1			0.1104
Mean LDL-c (mg/dL)	131	86.4	88.1	1.7	−2.5–6	0.42
% elevated LDL-c (>130 mg/dL)		5.3	7.6			0.4955
Mean HDL-c (mg/dL)	183	50.5	48.3	−2.2	−4.5–0.1	0.06
% decreased HDL-c (<40 mg/dL)		27.3	31.6			0.908
Mean TG (mg/dL)	202	96.5	103.3	6.6	−1.4–14.8	0.106
% elevated TG (>110 mg/dL)		29.5	37.6			0.005
Mean TC/HDL-c ratio	183	3.3	3.6	0.3	0.2–0.4	<0.001
% elevated TC/HDL-c ratio (>5)		5.5	9.8			0.121

TC, total cholesterol; LDL-c, low density lipoprotein cholesterol; HDL-c, high density lipoprotein cholesterol; TG, triglyceride.

^*At the time of enrolment into the study, after 12 months of stavudine containing ART.