Table 2. EC50s of insulin, insulin analogues and IGF1 for PIP₃ production in MCF-7 and MDA-MB231 cells.

	MCF-7	MDA-MB231
	EC50 (nM)	EC50 (nM)
Insulin	38.21±8.32	0.55±0.07
IGF1	0.44±0.08 **	0.71±0.10
Glargine	4.64±0.75 **	0.78±0.18
Detemir	164.68±104.42	2.30±0.18 **
Aspart	43.41±27.64	0.59±0.10
Glulisine	124.23±25.20 *	0.84±0.18
Lispro	58.48±25.90	0.43±0.13

Results are the means ± S.E.M. of 5 to 6 independent experiments.

^{*, **}, p<0.05 or p<0.01 respectively, when compared to insulin.