TABLE 3.

ADJUSTED RELATIVE HAZARDS OF CANCER MORTALITY ACCORDING TO HYPOXEMIA INDEX

Hypoxemia Index*	Relative Hazards of Cancer Mortality (95% CI)
Percentile < 73 (<0.8% of the time)	1.0
Percentile 73–89 (0.8–3.6% of the time)	1.6 (0.6–4.4)
Percentile 90–97 (3.6–11.2% of the time)	2.9 (0.9–9.8)
Percentile > 97 (>11.2% of the time)	8.6 (2.6–28.7)
P for trend	0.0008

Definition of abbreviations: AHI = apnea-hypopnea index; BMI = body mass index; CI = confidence interval.

Adjusted for age (time scale), sex, BMI, BMI², and smoking. Hypoxemia index = percent sleep time below 90% oxyhemoglobin saturation; analyses based on a subset of 1,306 participants on whom O₂ saturation data were available.

^*Cut-offs defined according to the same percentile distribution as that resulting from the standard AHI cut-offs used in this study (AHI = 5, 15, and 30).