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. 2012 Jul 26;345:e4800. doi: 10.1136/bmj.e4800

Table 1.

 Characteristics of studies

Study Design* Setting/data source Sample Outcomes Variables accounted for
Akerstedt et al, 2004 Retrospective cohort Swedish Living Conditions Survey 22 411 All cause mortality Age, stress, physically strenuous work, smoking, chronic disease
Alfredsson et al, 1985 Retrospective cohort Swedish census data 958 096 Myocardial infarction Age, county
Allesoe et al, 2011 Prospective cohort Danish Nurse Cohort Study 12 116 Coronary events Age, family history, diabetes, menopause, BMI, smoking, alcohol consumption, leisure time activity, physical activity at work
Babisch et al, 2005 Case-control 32 major hospitals in Berlin, Germany 4115 Myocardial infarction Age, diabetes, hypertension, family history, smoking, BMI, employment status, living without a partner, noise sensitivity, education, sex†, hospital†
Biggi et al, 2008 Retrospective cohort Municipal workers in Milan, Italy 468 Coronary events No covariate adjustment
Boggild et al, 1999 Prospective cohort Copenhagen Male Study 5207 Coronary events, all cause mortality Age, social class, sleep, tobacco, weight, height, fitness
Brown et al, 2009 Prospective cohort Nurses’ Health Study 80 108 Ischaemic stroke Age, questionnaire cycle, physical activity, BMI, alcohol, fruit and vegetable intake, menopausal status, smoking, hormone replacement, aspirin use, diabetes, coronary disease, blood pressure, serum cholesterol, husband’s education, snoring, sleep duration, atrial fibrillation
Ellingsen et al, 2007 Retrospective cohort Employees of fertilizer plant in Doha, Qatar 2562 Coronary and cardiovascular events No covariate adjustment
Falger and Schouten, 1992 Case-control Two large hospitals in Netherlands 458 Myocardial infarction Age, exhaustion, smoking, education, hospital site†
Fujino et al, 2006 Prospective cohort Survey data in Japan 17 649 Coronary, cardiovascular, cerebrovascular, and all cause mortality Age, smoking, alcohol, education, perceived stress, past medical history, BMI, hours of walking, hours of exercise, job type
Fukuoka et al, 2005 Case-control Five hospitals in Japan 94 Myocardial infarction Age†, work status†, sex†
Haupt et al, 2008 Retrospective cohort Survey data in West Pomerania, Germany 2510 Myocardial infarction Age, sex, food frequency score, socioeconomic status, smoking
Hermansson et al, 2007 Case-control Survey data in Sweden 607 Ischaemic stroke Age, smoking, education, job strain, BP, serum triglycerides, cholesterol, sex†, survey†, survey date†, locale
Hublin et al, 2010 Prospective cohort Population based twin cohort in Finland 20 142 Coronary mortality, cardiovascular events Age, marital status, social class, education, smoking, binge drinking, alcohol, hypertension, BMI, conditioning physical activity, life satisfaction, diurnal type, sleep length, use of hypnotics or tranquillisers, physical workload, working pace
Karlsson et al, 2005 Retrospective cohort Pulp and paper workers in Sweden 5442 Coronary, stroke related, and all cause mortality Age, duration of employment
Kawachi et al, 1995 Prospective cohort Nurses’ Health Study 79 109 Myocardial infarction, coronary events, coronary and all cause mortality, cardiovascular events Age, smoking, diabetes, hypertension, hypercholesterolaemia, past oral contraceptive use, current use of hormonal replacement, parental MI before age 60, alcohol, physical activity, BMI, aspirin use, fifths of vitamin E, follow-up period, husband’s education
Knutsson et al, 1986 Prospective cohort Pulp and paper works in Sweden 504 Coronary events Age, duration of exposure, smoking, family status
Knutsson et al, 1999 Case-control Survey data in Sweden 4648 Myocardial infarction Age†, sex†, residence†, smoking, job strain, education
Koller, 1983 Retrospective cohort Oil refinery workers in Austria 301 Coronary and cardiovascular events Age†, duration of employment†
Laugsand et al, 2011 Prospective cohort Nord-Trøndelag Health Study (survey in Norway) 52 610 Myocardial infarction Age, sex, marital status, education, shift work, systolic blood pressure, total cholesterol, diabetes mellitus, BMI, physical activity, smoking, depression, poor sleep
Liu and Tanaka, 2002 Case-control 22 hospitals in Japan 705 Myocardial infarction Age†, sex†, residence†
McNamee et al, 1996 Case-control Nuclear plant workers 934 Coronary mortality Age†, smoking, BMI, height, systolic BP, diastolic BP, job status, duration of employment, year of starting work†
Netterstrom et al, 1999 Case-control Two Danish hospitals 252 Myocardial infarction Age†, sex†
Rafnsson and Gunnarsdottir, 1990 Retrospective cohort Fertiliser plant workers in Iceland 603 Coronary and all cause mortality Age, calendar year
Steenland and Fine, 1996 Case-control Heavy equipment plant workers (US) 944 Coronary mortality Age, worksite, race
Tarumi, 1997 Retrospective cohort Japanese steel industry workers 9141 Cardiovascular and all cause mortality Age, job site location, blue collar status†
Taylor and Pocock (reanalysed by Knutsson et al, 2004) Retrospective cohort 10 industrial organisations in Britain 8767 Coronary and cerebrovascular mortality, cardiovascular and total mortality Age, calendar period, sex†
Taylor et al, 1972 Retrospective cohort 29 industrial organisations in Britain 1930 Cardiovascular events Age†, organisation†, occupation†
Tuchsen, 1993 Prospective cohort Danish survey data 406 969 Coronary events Age, sex†
Tuchsen et al, 2006 Prospective cohort Danish survey data 5517 Coronary and cardiovascular events Annoying noise, coldness, conflicts at work, high cognitive demands, ergonomic exposure, job insecurity, passive smoking, monotonous tasks, low decision authority, heat, walking or standing for long hours at work, low social support, BMI, current smoking
Vertin, 1978 Prospective cohort Viscose rayon factory workers 200 Coronary events Carbon disulfide exposure†
Virkunnen et al, 2006 Prospective cohort Helsinki Heart Study (clinical trial) 1804 Coronary events Age, smoking, systolic BP, cholesterol, BMI, gemfibrozil use, noise, physical workload
Virtanen and Notkola, 2002 Retrospective cohort Finnish census data 385 500 Cerebrovascular and cardiovascular mortality Age, marital status, professional status, education, income, socioeconomic status, job exposure variables
Yadegarfar and McNamee, 2008 Case-control Nuclear plant workers in Britain 1270 Coronary mortality Age†, year of starting work†, smoking, systolic BP, diastolic BP, BMI, height, work status, duration employment, social class

BMI=body mass index; BP=blood pressure.

*All studies used day workers as comparison group, with four exceptions that used general population controls—Alfredsson et al, Rafnsson et al, Taylor et al, and Tuchsen 1993.

†Matching or stratifying variable.