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Exogenous addition of lyso-phosphatidylglucoside induces growth cone collapse of rat DRG neurons. DRG neurons were isolated from an E12.5 rat. Actin filaments were visualized with rhodamine-labeled phalloidin (M. Yamazaki et al., unpublished data). A, Control; B, LPA (100 µM); C, lyso-PtdGlc (10 µM). The lyso form of PtGlc showed more potent activity for growth cone collapse.
