Fig. 2.

Schematic diagram showing the design of the RALI-DHF study. RALI-DHF Ranolazine in Diastolic Heart Failure; NYHA New York Heart Association class; EF ejection fraction; LVEDP left ventricular end diastolic pressure; NT-proBNP N-terminal pro–B-type natriuretic peptide; ECG electrocardiogram; Echo echocardiogram; CPET cardiopulmonary exercise testing; Pat patient; i.v. intravenous; PCWP pulmonary capillary wedge pressure; PAP pulmonary artery pressure; SVR systemic vascular resistance; PVR pulmonary vascular resistance; dP/dt; rate of pressure change in the ventricle