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. Author manuscript; available in PMC: 2012 Jul 27.
Published in final edited form as: J Immunol. 2010 Apr 26;184(11):6327–6334. doi: 10.4049/jimmunol.0904043

Figure 8. Cytokines are released from human eosinophils in response to PAF, but not lysoPAF.

Figure 8

Cytokines released in response to 5 μM PAF (gray bars) or lysoPAF (black bars) or DMSo control (white bars) include (A) platelet-derived growth factor-bb (B) interleukin-1 receptor antagonist (C) interleukin-13 (D) eotaxin-1 (E) fibroblast growth factor basic (FGF-basic), (F) interleukin-9 (IL-9) (F), (G) RANTES / CCL5. Data collected from two independent donors, each assayed in triplicate. (H) RANTES / CCL5 release in response to 5 μM PAF or lysoPAF in absence and presence of 10 μM PAFR antagonists, pooled data from 9-12 separate donors. (I) RANTES / CCL5 release in response to 5 μM PAF in the presence or absence of 5 μg/mL cycloheximide. Significance determined by 1-way ANOVA followed by Tukey’s multiple comparison; * p<0.05, ** p<0.01, *** p<0.001.