Table 2.
Immune response to gliadin and 33-mer after the in-vivo wheat challenges
| 1st challenge | 2nd challenge | |||||||
|---|---|---|---|---|---|---|---|---|
| Gliadin | 33-mer | Gliadin | 33-mer | |||||
| ΔSFC† | FI‡ | ΔSFC† | FI‡ | ΔSFC† | FI‡ | ΔSFC† | FI‡ | |
| Pt 1 | 25 | 25 | 0 | 1 | 233 | 234 | 0 | 1 |
| Pt 2 | 368 | 11·5 | 81 | 81 | 69 | 1·4 | 164 | 5·1 |
| Pt 3 | 29 | 1,9 | 17 | 17 | 10 | 10 | 0 | 1 |
| Pt 4 | 0 | 0·14 | 0 | 0 | 56 | 1·3 | 0 | 0·7 |
| Pt 5 | 58 | 8·2 | 139 | 139 | 81 | 5,3 | 0 | 1 |
| Pt 6 | 56 | 56 | 148 | 148 | 0 | 0·9 | 11 | 12 |
| Pt 7 | 83 | 1·8 | 221 | 2,9 | 24 | 1·2 | 104 | 2·5 |
| Pt 8 | 130 | 15·4 | 77 | 77 | n.d. | n.d | n.d. | n.d. |
| Pt 9 | 225 | 16 | 0 | 0 | 0 | 1 | 14 | 14 |
| Pt 10 | 32 | 2·4 | 8 | 8 | 328 | 1·6 | 0 | 3 |
| Pt 11 | 16 | 2·6 | 22 | 22 | 343 | 8·6 | 7 | 7 |
| Pt 12 | 0 | 1 | 0 | 0 | 47 | 1·5 | 4 | 4 |
| Pt 13 | 131 | 10 | 79 | 79 | 0 | 0·4 | 0 | 0·8 |
| Pt 14 | 88 | 2·1 | 167 | 167 | 1 | 1·1 | 2 | 2 |
†
ΔSFC (spot-forming cells): net interferon (IFN)-γ SFC detected on day 6 minus net IFN-γ SFC detected on day 0.
‡
FI (fold increase): net IFN-γ SFC in response to gliadin/peptide 33-mer observed on day 6 divided by the net IFN-γ SFC observed on day 0; n.d., not done.