Table 2.
Summary of the study results
| LAIR-1 | SIRL-1 | CD31 | SIRPα | Siglec-9 | CD200 | CD200R | IREM-1 | |
|---|---|---|---|---|---|---|---|---|
| Cord blood | ||||||||
| Neutrophils | ↑ | = | = | = | ↑** | = | = | |
| Monocytes CD16– | = | = | = | = | = | = | ↓*** | |
| Monocytes CD16+ | = | = | = | = | = | = | ↓* | |
| NK cells | = | = | ||||||
| CD4+CD45RO– T cells | ↑* | ↑*** | ↑*** | |||||
| CD4+CD45RO+ T cells | ↑*** | ↑** | ↑*** | |||||
| CD8+CD45RO– T cells | ↑** | ↑*** | ||||||
| CD8-CD45RO– T cells | ↑*** | ↑*** | ↑*** | |||||
| B cells | ↑*** | ↑** | = | ↓** | ||||
| Neonatal venous blood | ||||||||
| Neutrophils | ↑** | = | = | = | = | = | = | |
| Monocytes CD16– | ↓* | = | = | = | = | = | = | |
| Monocytes CD16+ | = | = | = | = | = | = | = | |
| NK cells | = | ↓*** | ||||||
| CD4+CD45RO– T cells | ↑* | ↑* | = | |||||
| CD4+CD45RO+ T cells | ↑*** | = | ↑*** | |||||
| CD8+CD45RO– T cells | ↑** | ↑*** | ||||||
| CD8+CD45RO– T cells | ↑*** | ↑*** | ↑** | |||||
| B cells | ↑*** | = | ↓* | ↓*** |
P-values are the outcome of one-way analysis of variance (anova) with post-hoc Bonferroni correction (*P < 0·05; **P < 0·01; ***P < 0·001). Shows the expression of each inhibitory receptor per cell type as increased, decreased or similar compared to adult cells. Where no symbol is shown, a receptor was not expressed on that cell type. LAIR-1, leucocyte-associated immunoglobulin (Ig)-like receptor-1; SIRL-1, signal inhibitory receptor on leucocytes-1; SIRPα, signal-regulatory protein alpha; IREM-1, immune receptor expressed on myeloid cells-1; NK, natural killer.