A, top, representative sweeps of single-channel currents of the L-VDCC before (left) and during (right) DHPG application. Bottom, representative plots of single-channel open probability (left) and current amplitude (right) in the experiment examining the effect of the DHPG application (horizontal bar). B, summary of the DHPG-induced change in single-channel current amplitude (left), open probability (middle) and median of open time (right) (n= 8). Calibration: 1 pA, 50 ms.