Table II.
Low and high level of hTERT methylation in tumor and normal colorectal tissues.
| Met <25 (%) | Met ≥25 (%) | Total (%) | |
|---|---|---|---|
| Tumor mucosa | |||
| TA− | 0 (0) | 2 (18) | 2 (18) |
| TA+ | 1 (9) | 8 (73) | 9 (82) |
| Total | 1 (9) | 10 (91) | 11 (100) |
| Transitional mucosa | |||
| TA− | 2 (18) | 3 (27) | 5 (45) |
| TA+ | 1 (9) | 5 (46) | 6 (55) |
| Total | 3 (27) | 8 (73) | 11 (100) |
| Normal mucosa | |||
| TA− | 4 (36) | 3 (27) | 7 (64) |
| TA+ | 3 (27) | 1 (9) | 4 (36) |
| Total | 7 (64) | 4 (36) | 11(100) |
The level is considered as low when the percentage of hTERT methylation (Met) was <25% and as high when the percentage was >25%. Telomerase activity was measured in arbitrary units. Met, hTERT methylation; TA, telomerase activity.